Publications
Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer. J L Galeano Niño, H Wu, K D. LaCourse, A G. Kempchinsky, A Baryiames, B Barber, N Futran, J Houlton, C Sather, E Sicinska, A Taylor, S S. Minot, C D. Johnston* & S Bullman*.
Nature (2022). https://doi.org/10.1038/s41586-022-05435-0 View Article
The cancer chemotherapeutic 5-fluorouracil is a potent inhibitor of Fusobacterium nucleatum and its activity is modified by the intratumoral microbiota. K D. LaCourse, M Zepeda Rivera, A Baryiames, A G. Kempchinsky, CD. Johnston*& Susan Bullman*.
Cell Reports (2022) https://doi.org/10.1016/j.celrep.2022.111625 View Article 
Genomic Stability and Genetic Defense Systems in Dolosigranulum pigrum a Candidate Beneficial Bacterium from the Human Microbiome. Flores Ramos S, Brugger S. D.,Escapa IF, Skeete C A., Cotton S L., Eslami S M., Gao W, Bomar L, Tran TH., Jones DS., Minot S, Roberts RJ., Johnston CD., Lemon KP. mSystems; September/October 2021 Volume 6 Issue 5 e00425-21 View article
The Relationship Between Gastrointestinal Cancers and the Microbiota. LaCourse KD., Johnston CD. Bullman. S. Lancet Gastroenterol Hepatol. 2021 Jun;6(6):498-509. doi: 10.1016/S2468-1253(20)30362-9. Epub 2021 Mar 18.
Complete Genome Sequences and Methylome Analyses of Cutibacterium acnes subsp. acnes Strains DSM 16379 and DSM 1897T. , , , , CD,
Insights Obtained by Culturing Saccharibacteria With Their Bacterial Hosts. B Bor, AJ Collins, PP Murugkar, S Balasubramanian, TT To, EL Hendrickson, JK Bedree, FB Bidlack, CD Johnston, W Shi, JS McLean, X He, FE Dewhirst. Journal of Dental Research. Feb 19, 2020.
Systematic evasion of the restriction-modification barrier in bacteria. Johnston CD, , SR, , , , and View article
Biosensor libraries harness large classes of binding domains for construction of allosteric transcriptional regulators. Juárez JF, Lecube-Azpeitia B, Brown SL, Johnston CD, Church GM. Nature Communications DOI: 10.1038/s41467-018-05525-6 View PDF
Restriction-modification mediated barriers to exogenous DNA uptake and incorporation employed by Prevotella intermedia. Johnston CD, Skeete CA, Fomenkov A, Roberts RJ, Rittling SR. (2017) PloS One 12(9):e0185234. View PDF
Modulation of infection-mediated migration of neutrophils and CXCR2 trafficking by osteopontin. Singh R, Hui T, Matsui A, Allahem Z, Johnston CD, Ruiz-Torruella M, Rittling SR. (2017) Immunology 150(1):74-86. View PDF
Genome analysis of Cronobacter phage vB_CsaP_Ss1 reveals an endolysin with potential for biocontrol of Gram-negative bacterial pathogens. Endersen L, Guinane CM, Johnston CD, Neve H, Coffey A, Ross RP, McAuliffe O, O’Mahony J. (2015) The Journal of General Virology 96(Pt 2):463-77. View PDF
Pathogenic bacterial species associated with endodontic infection evade innate immune control by disabling neutrophils. Matsui A, Jin JO, Johnston CD, Yamazaki H, Houri-Haddad Y, Rittling SR. (2014) Infection and Immunity 82(10):4068-79. View PDF
Enhanced expression of codon optimized Mycobacterium avium subsp. paratuberculosis antigens in Lactobacillus salivarius. Johnston CD, Bannantine JP, Govender R, Endersen L, Pletzer D, Weingart H, Coffey A, O’Mahony J, Sleator RD. (2014) Frontiers in Cellular and Infection Microbiology 4:120. View Article
The role of the Cronobacter sakazakii ProP C-terminal coiled coil domain in osmotolerance. Feeney A, Johnston CD, Lucid A, O’Mahony J, Coffey A, Lucey B, Sleator RD. (2014) Gut Pathogens 6(1):46. View PDF
Analysis of the role of the Cronobacter sakazakii ProP homologues in osmotolerance. Feeney A, Johnston CD, Govender R, O’Mahony J, Coffey A, Sleator RD. (2014) Gut Pathogens 6:15. View PDF
Codon optimisation to improve expression of a Mycobacterium avium ssp. paratuberculosis-specific membrane-associated antigen by Lactobacillus salivarius. Johnston CD, Douarre PE, Soulimane T, Pletzer D, Weingart H, MacSharry J, Coffey A, Sleator RD, O’Mahony J. (2013) Pathogens and Disease 68(1):27-38. View Article
Development of a novel oral vaccine against Mycobacterium avium paratuberculosis and Johne’s disease: a patho-biotechnological approach. Johnston CD, Coffey A, O’ Mahony J, Sleator RD. (2010) Bioengineered Bugs 1(3):155-63. View PDF
Funding
Our research would not be possible without support from:
Johnston Lab 