Publications

Genomic Stability and Genetic Defense Systems in Dolosigranulum pigrum a Candidate Beneficial Bacterium from the Human Microbiome. Flores Ramos S, Brugger S. D.,Escapa IF, Skeete C A., Cotton S L., Eslami S M., Gao W, Bomar L, Tran TH., Jones DS., Minot S, Roberts RJ., Johnston CD., Lemon KP. mSystems; September/October 2021  Volume 6  Issue 5  e00425-21 View article

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The Relationship Between Gastrointestinal Cancers and the Microbiota. LaCourse KD., Johnston CD. Bullman. S. Lancet Gastroenterol Hepatol​. 2021 Jun;6(6):498-509. doi: 10.1016/S2468-1253(20)30362-9. Epub 2021 Mar 18. 

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Complete Genome Sequences and Methylome Analyses of Cutibacterium acnes subsp. acnes Strains DSM 16379 and DSM 1897T. Deptula P, Laine P, Paulin L, Auvinen P, Roberts RJ, Johnston CD, Varmanen. P. Microbiol Resour Announc; 9(29):e00705-20. doi: 10.1128/MRA.00705-20. Jul 16, 2020 

Insights Obtained by Culturing Saccharibacteria With Their Bacterial Hosts. B Bor, AJ Collins, PP Murugkar, S Balasubramanian, TT To, EL Hendrickson, JK Bedree, FB Bidlack, CD Johnston, W Shi, JS McLean, X He, FE Dewhirst. Journal of Dental Research. Feb 19, 2020.

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Systematic evasion of the restriction-modification barrier in bacteria. Johnston CDCotton SLRittling SRStarr JRBorisy GGDewhirst FE, and Lemon KP. Proceedings of the National Academy of Sciences, PNAS, View article

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Biosensor libraries harness large classes of binding domains for construction of allosteric transcriptional regulators. Juárez JF, Lecube-Azpeitia B, Brown SL,  Johnston CD,  Church GM. Nature Communications DOI: 10.1038/s41467-018-05525-6 View PDF

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Restriction-modification mediated barriers to exogenous DNA uptake and incorporation employed by Prevotella intermedia. Johnston CD, Skeete CA, Fomenkov A, Roberts RJ, Rittling SR. (2017) PloS One 12(9):e0185234. View PDF

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Modulation of infection-mediated migration of neutrophils and CXCR2 trafficking by osteopontin. Singh R, Hui T, Matsui A, Allahem Z, Johnston CD, Ruiz-Torruella M, Rittling SR. (2017) Immunology 150(1):74-86. View PDF

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Genome analysis of Cronobacter phage vB_CsaP_Ss1 reveals an endolysin with potential for biocontrol of Gram-negative bacterial pathogens. Endersen L, Guinane CM, Johnston CD, Neve H, Coffey A, Ross RP, McAuliffe O, O’Mahony J. (2015) The Journal of General Virology 96(Pt 2):463-77. View PDF

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Pathogenic bacterial species associated with endodontic infection evade innate immune control by disabling neutrophils. Matsui A, Jin JO, Johnston CD, Yamazaki H, Houri-Haddad Y, Rittling SR. (2014)  Infection and Immunity 82(10):4068-79. View PDF

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Enhanced expression of codon optimized Mycobacterium avium subsp. paratuberculosis antigens in Lactobacillus salivarius. Johnston CD, Bannantine JP, Govender R, Endersen L, Pletzer D, Weingart H, Coffey A, O’Mahony J, Sleator RD. (2014)  Frontiers in Cellular and Infection Microbiology 4:120. View Article

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The role of the Cronobacter sakazakii ProP C-terminal coiled coil domain in osmotolerance. Feeney A, Johnston CD, Lucid A, O’Mahony J, Coffey A, Lucey B, Sleator RD. (2014)  Gut Pathogens 6(1):46. View PDF

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Analysis of the role of the Cronobacter sakazakii ProP homologues in osmotolerance. Feeney A, Johnston CD, Govender R, O’Mahony J, Coffey A, Sleator RD. (2014) Gut Pathogens 6:15. View PDF

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Codon optimisation to improve expression of a Mycobacterium avium ssp. paratuberculosis-specific membrane-associated antigen by Lactobacillus salivarius. Johnston CD, Douarre PE, Soulimane T, Pletzer D, Weingart H, MacSharry J, Coffey A, Sleator RD, O’Mahony J. (2013) Pathogens and Disease 68(1):27-38. View Article

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Development of a novel oral vaccine against Mycobacterium avium paratuberculosis and Johne’s disease: a patho-biotechnological approach. Johnston CD, Coffey A, O’ Mahony J, Sleator RD. (2010)  Bioengineered Bugs 1(3):155-63. View PDF

Funding 

Our research would not be possible without support from:download.jpg

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